详细介绍
品牌 | 其他品牌 | 产地类别 | 国产 |
---|---|---|---|
应用领域 | 医疗卫生 |
全身体积描记系统(兔、犬)产品描述
全身体积描记系统(兔、犬)(whole-bodyplethysmograph,WBP)可以对清醒自由活动的大动物进行肺功能及气道反应相关的测试,避免了创伤性气管切开术及麻醉的影响,使实验过程简便快捷,并适合长期跟踪研究。
塔望科技开发的全身体积描记系统,除了做小鼠、大鼠/豚鼠外,另外还提供大动物的测试舱,如兔子、犬、猴等。
全身体积描记系统(兔、犬)产品特点
· 适用动物:兔子、犬
· 不需要做手术,操作简单
· 可在动物在自然状态下呼吸的研究以及长期跟踪实验,适合进行药物初筛
· 具有药物气溶胶雾化模块
· 具有自动标定功能
· 可提供食槽,进行长期连续监测
· 可选配测量心电、血压、体温、心率等指标,可与植入式遥测设备联合使用
· 具有分析软件,数据可保存至excel或txt格式
全身体积描记系统(兔、犬)检测参数
Ti:吸气时间(s)
Te:呼气时间(s)
PIF:最大吸气流速(ml/s)
PEF:最大呼气流速(ml/s)
Volbal:吸气时间/呼气时间
F:呼吸频率(次/min)
Vt:潮气量(ml)
Mv:分钟通气量(ml)
AV:累积体积(ml)
EF50:呼出50%气量时对应的呼气流速(ml/s)
EIP:吸气峰值压力(仅在侵入式法测量时有效)
EEP:呼气峰值压力(仅在侵入式法测量时有效)
TR:松弛时间
PenH:增强呼气间歇(enhanced pause)
Rpef:相对时间
全身体积描记系统(兔、犬)适用领域
各种呼吸疾病研究,如:哮喘、肺纤维化、肺损伤、ARDS、肺癌等
安全药理:药物对呼吸系统的影响
睡眠呼吸:监测动物低通气、阻塞性呼吸暂停等
环境毒理:环境污染物对动物呼吸的影响
吸入式毒理:染毒物质对呼吸系统的毒性影响
高原医学:高原环境对呼吸系统的影响
其它需要对呼吸参数评价的场合
全身体积描记系统(兔、犬)型号说明
名称 | 型号 | 说明 | 单位 |
大动物全身体积描记系统 | WBP-P | 适用于猕猴、食蟹猴 | 套 |
大动物全身体积描记系统 | WBP-T | 适用于兔子 | 套 |
全身体积描记系统(兔、犬)用户名单
上海市中心医院 | 瑞金医院 | 复旦大学附属华山医院 | 上海药物所 |
中国药科大学 | 广东药科大学 | 重庆医科大学 | 成都市第三人民医院 |
北京中医药大学 | 中科院城市环境研究所 | 南京大学 | 四川大学华西医院 |
苏州大学 | 中医药大学 | 安徽医科大学第一附属医院 | 青岛市市立医院 |
兰州大学 | 南华大学 | 宁夏医科大学 | ...... |
全身体积描记系统(兔、犬)相关文献
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[4]Yumei Zhou, Haihong Zhao, Tieshan Wang, Xiaoshan Zhao, Ji Wang and Qi Wang, " Anti-Inflammatory and Anti-asthmatic Effects of TMDCT Decoction in Eosinophilic Asthma Through Treg/ Th17 Balance" [J].Frontiers, 2022.819728:
[5]Yumei Zhou, Tieshan Wang, Xiaoshan Zhao, Ji Wang and Qi Wang, "Plasma Metabolites and Gut Microbiota Are Associated With T cell Imbalance in BALB/c Model of Eosinophilic Asthma" [J].Frontiers, 2022. 819747:
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[9]Jiawen Zhou, Haiyun Chen, Qiuyi Wang, Sihan Chen, Rong Wang, Ziyang Wang, Cuicui Yang, Ao Chen, Jingyu Zhao, Zihao Zhou, Zhiyuan Mao, Guoping Zuo, Dengshun Miao, Jianliang Jin. "Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription" [J].Aging CellVolume 21, Issue 8 e13680
[10]Yapeng, LuPanpanChang, WangwangDing, JiangpeiBian, DanWang, XuetingWang, QianqianLuo, XiaomeiWu, LiZhu. "Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells" [J].European Journal of Pharmacology, Volume 929, 15 August 2022, 175137
[11]Mengjun Zhanga, Huiyang Jiang, Lan Wu, Haoyu Lu, Hriday Bera, Xing Zhao, Xiong Guo, Xulu Liu, Dongmei Cun, Mingshi Yang. "Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment" [J]. Journal of Controlled Release, Volume 352
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